CKD is often symptom-free until the later stages. When symptoms do appear, they're caused by the build-up of waste products and fluid, and the knock-on effects on other body systems.
😴 Fatigue
One of the most common symptoms. Caused by anaemia (low red blood cells) due to reduced EPO production.
💧 Swelling
Fluid retention causes swelling in the ankles, legs, and around the eyes — especially in the morning.
💨 Breathlessness
Fluid can build up around the lungs. Breathlessness at rest is a sign to contact your renal team promptly.
🤢 Nausea
Waste products building up in the blood (uraemia) can cause nausea, vomiting and loss of appetite.
🔴 Itching
High phosphate and the build-up of waste products causes skin itching (pruritus), often worse at night.
🧠 Brain fog
Difficulty concentrating, memory problems and feeling mentally slow — caused by uraemia and anaemia.
🦵 Cramps
Imbalances in calcium, potassium and sodium cause muscle cramps, often in the legs at night.
🫀 High blood pressure
Damaged kidneys release too much renin, raising blood pressure — which in turn causes further kidney damage.
⚠️ Contact your renal team or GP urgently if you have: sudden breathlessness at rest, severe swelling, chest pain, confusion, very little urine output, or potassium symptoms (muscle weakness, palpitations).